A comprehensive service and support program to help eligible patients get access to medications and services, and help physician offices, too.

The IPSEN CARES® program was designed to simplify the process of applying for and getting coverage for Somatuline® Depot (lanreotide) Injection. By serving as a central point of contact between you, your patients, insurance companies, and specialty pharmacies, IPSEN CARES can save your office valuable time and energy. The IPSEN CARES program provides online and PDF forms to help your staff get patients efficiently enrolled and authorized; provides information on copay programs and other financial assistance; and helps coordinate home delivery and home injection services.


Or call 1-866-435-5677, Monday-Friday, 8am-8pm ET (5am-5pm PT)

HCP Resource Guide

The Somatuline® Depot Resource Guide contains important information to help you with purchasing, billing, coding and reimbursement, plus more details and FAQs for IPSEN CARES.

Download Somatuline® Depot Resource guide to acquisition, billing, coding & reimbursement.

Community organizations that provide acromegaly patients with information and support

National Endocrine and Metabolic Diseases Information Service

A service of the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), National Institutes of Health (NIH)

Pituitary Network Association

Learn more about pituitary disorders, get contact information about hormonal health hospitals near you, and get answers to frequently asked questions.

Important Safety Information and Indication


Somatuline® Depot (lanreotide) Injection is contraindicated in patients with hypersensitivity to lanreotide. Allergic reactions (including angioedema and anaphylaxis) have been reported following administration of lanreotide.


  • Cholelithiasis and Gallbladder Sludge: Somatuline Depot may reduce gallbladder motility and lead to gallstone formation. Periodic monitoring may be needed
  • Hypoglycemia or Hyperglycemia: Pharmacological studies show that Somatuline Depot, like somatostatin and other somatostatin analogs, inhibits the secretion of insulin and glucagon. Blood glucose levels should be monitored when Somatuline Depot treatment is initiated, or when the dose is altered, and antidiabetic treatment should be adjusted accordingly
  • Thyroid Function: Slight decreases in thyroid function have been seen in acromegalic patients during treatment, though clinical hypothyroidism is rare (<1%). Thyroid function tests are recommended where clinically indicated
  • Cardiac Abnormalities: Somatuline Depot may decrease heart rate. In cardiac studies with acromegalic patients, the most common cardiac adverse reactions were sinus bradycardia, bradycardia, and hypertension. In patients without underlying cardiac disease, Somatuline Depot may lead to a decrease in heart rate without necessarily reaching the threshold of bradycardia. In patients suffering from cardiac disorders prior to treatment, sinus bradycardia may occur. Care should be taken when initiating treatment in patients with bradycardia
  • Drug Interactions: The pharmacological gastrointestinal effects of Somatuline Depot may reduce the intestinal absorption of concomitant drugs. Concomitant administration of Somatuline Depot may decrease the relative bioavailability of cyclosporine and may necessitate the adjustment of cyclosporine dose to maintain therapeutic levels


The most common adverse reactions (incidence >5%) were diarrhea (37%), cholelithiasis (20%), abdominal pain (19%), nausea (11%), injection-site reactions (9%), constipation (8%), flatulence (7%), headache (7%), arthralgia (7%), vomiting (7%), and loose stools (6%).


Patients with moderate and severe renal impairment or moderate and severe hepatic impairment: Initial dose is 60 mg every 4 weeks.


Somatuline Depot is a somatostatin analog (SSA) indicated for the long-term treatment of patients with acromegaly who had an inadequate response to or cannot be treated with surgery and/or radiotherapy.

Click here for Full Prescribing Information.

Somatuline Depot is available in 60 mg, 90, mg and 120 mg

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Somatuline® Depot (lanreotide) Injection is contraindicated in patients with hypersensitivity to lanreotide. Allergic reactions (including angioedema and anaphylaxis) have been reported following administration of lanreotide.

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PRIOR TREATMENT STATUS (refers to medication only)

Study included a diverse range of patient types2

NOTE: Patients either were not candidates for surgery or had had surgery and required further control.

The procedure for injecting Somatuline® Depot (lanreotide) Injection used for treating acromegaly is explained in this illustration.

Device not shown at actual size

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